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Darren McGavin is cast as Viktor Karmak, an old enemy of U.N.C.L.E. agents Solo and Illya. Kidnapping Illya, Karmak lures Solo into a condemned and heavily boobytrapped 12-block section of Manhattan. Enlisting the aid of avant-garde artist Sheila Van Tillson (Marlyn Mason) in rescuing Illya, Solo, and the girl find themselves being hunted by Karmak and his ferocious pet cheetah. Filmed almost exclusively on MGM's fabled "New York Street," "The Deadly Quest Affair" was written by Robert E. Thompson, and originally broadcast on October 30, 1967.