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Two mismatched lovers struggle to find happiness in an unaccepting society in this drama. Marie (Denisa Demeterova) is a woman of Romany heritage (known to many as Gypsies) who works at a hospital in the Czech Republic. Marie wants to quietly assimilate into the culture around her, a notion that offenders her brother Tibor (Koloman Balaz), who is proud of is Romany blood and must often defend himself against insults from his co-workers at a sawmill. One of Tibor's greatest antagonists is Wagan (Petr Lnenicka), who is friends with Frantisek (Tomas Masopust), another sawmill employee with a passionate interest in Native American culture. Frantisek meets Marie by chance, and an immediate attraction blooms between them; however, Marie is already engaged to Martin (Mirek Kotlar), and Tibor will not hear of her leaving her fiancée for a Czech, especially one who is friends with Wagan. Frantisek discovers Wagan and his other friends are no more accepting of Marie, but their ridicule doesn't change the way he feels about her. India & Sestricka (aka The Indian and the Nurse) was the first feature film from director Dan Wlodarczyk.