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After discovering that her lover Paul Clements (Ed Nelson) is married, Ruth Norton (Pamela Tiffin) angrily jumps into her car and speeds away--striking down a pedestrian in the process. The victim turns out to be fugitive from justice Richard Kimble (David Janssen), whom the distraught Ruth takes to her home to recover from his injuries. In his delirium, Kimble recalls the events leading up to the murder of his wife Helen (Diane Brewster) by the elusive One-Armed Man (Bill Raisch)--and also unwittingly reveals that he had plenty of motive to commit the murder himself.