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Two former stars of Melrose Place reunite for this story that trades in soap opera glamour for the grittier thrills of a psychological crime thriller. Karen (Daphne Zuniga) was born to a wealthy family and has never quite found her way out from under the wings of her overprotective parents. Karen is seeing an analyst, but she's also having an affair with him -- which does not make her unusual among his female patients. When her psychiatrist/lover is killed after one of her appointments, Karen becomes the police's prime suspect; she decides to play with the truth and tells the police that she can no longer remember what happened that day. On the advice of her lawyer, Karen begins working with another psychiatrist, Dr. Peter Rexler (Jack Wagner), in hope that he can help her recover her memories of her last meeting with the doctor. But Karen's forgetful act works all too well when Peter, unable to get to the bottom of her repressed memories, has her institutionalized. Artificial Lies also stars Stewart Bick, Maxim Roy, and Claudia Ferri.