AllMovie

With Vacation in Reno, RKO contract actress Anne Jeffreys proved herself an accomplished comedienne, a fact verified by her later work on TV's Topper. Jeffreys is cast as Eleanor, the wife of would-be prospector Jack Carroll (Jack Haley). When hubby goes off to find a cache of hidden loot near Reno, Eleanor becomes convinced that he's actually gone to the Nevada city to secure a quickie divorce. She trails him to a dude ranch on the outskirts of Reno, where Jack has somehow gotten mixed up with a gang of thick-witted bank robbers (Morgan Conway, Alan Carney, Iris Adrian). No opportunity for a slapstick setpiece is ignored throughout the film, culminating with the inevitable "wild ride" through the desert.