Synopsis by Hal Erickson
Marguerite Bertsch, one of Vitagraph's busiest screenwriters, was responsible for the three-reel "melodramatic farce" Uncle Bill. The title character, played by Donald Hall, is the wealthy relative of bickering married couple John and Julia Mason (William Humphrey, Julia Swayne Gordon). A burglar named Oiley Curley (Jack Brawn) is mistakenly identified as Uncle Bill, an error which he intends to use to his advantage. Meanwhile, the real Uncle Bill falls head over heels in love with cute young Gladys (Constance Talmadge), who happens to be Julia's sister. Billy Quirk, a popular comedian of the era, is the "mutual friend" character who ends up tying all the loose plot strands together.