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Though Larry vehemently refuses to admit that he has a problem, Artie (Rip Torn) and Roseanne stage an intervention after realizing that Larry's (Garry Shandling) addiction to painkillers is spiraling out of control. While Artie and Roseanne hold Larry at home and force him to quit cold turkey, suspicions around the office are aroused when Pat Sajak sits in for Larry during his week-long convalescence. Roseanne forces Larry to come clean with his crew, but their supportive display is spiked with cynicism when Paula (Janeane Garofalo) wins the office pool with her speculation that Larry's absence was drug-related. As Larry returns to the office longing for the company of Roseanne, the two express their feelings for one another over lunch, leading to an unexpected kiss and a proposal from Larry.