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Smash-Up on Interstate 5 is a 1976 American made-for-television disaster film directed by John Llewellyn Moxey. Loosely based on the novel Expressway written by Trevor Dudley-Smith under the pseudonym Howard North, the film chronicles the aftermath of a 39-car smash-up in California. The Highway Patrol Office used in the film is California Highway Patrol Office 575 located at 2130 Windsor Avenue, Altadena, California 91001.