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Though he'd intended to retire when talkies came in, silent-screen matinee idol Thomas Meighan kept returning to the screen by popular demand until 1934, two years before his death. In Skyline, Meighan is cast as James McClellan, a builder specializing in Manhattan skyscrapers. Though fiercely independent, McClellan generously takes on talented young architect John Breen (Hardie Albright) as his partner, nurturing his protégé into a successful career of his own. What McClellan knows, but Breen doesn't, is that the younger man is McClellan's illegitimate son. Before McClellan reveals the truth, there is an unpleasant story twist when Breen falls in love Paula Lambert (Myrna Loy), his father's mistress. Part and parcel of the film's happy ending is Breen's romance with ingenue Kathleen Kearney (Maureen O'Sullivan). Skyline is based on East Side, West Side, a novel by Felix Riesenberg.