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British character actor Lionel Atwill, in his final performance, appeared as a power-mad Englishman attempting to rule the world in this 13 chapter Universal serial. Sir Eric Hazarias (Atwill) is searching the mountains of Himalaya for Metorium 245, the only known antidote to the Bomb. Sir Eric is opposed by United Peace Foundation investigator Rod Stanton (Russell Hayden of Hopalong Cassidy fame); scientist daughter Marjorie Elmore (Jane Adams, who had been so memorable as the hunchbacked nurse in House of Dracula); and a local guide, Tal Shen (Keye Luke, Charlie Chan's number one son). Midway through the serial, the British megalomaniac steps in the background in favor of the even more nefarious Malborn (John Mylong), "the power in back of Sir Eric." The sad reason for this sudden change of direction was the fact that Atwill was dying of bronchial cancer (he died April 22, 1946). Bits of dialogue filmed earlier were inserted, and actor George Sorel doubled Atwill in several scenes, Sir Eric's trademark Panama hat pulled well down over his face. In an economy move, The Lost City of the Jungle used stock footage from Columbia's earlier Lost Horizon, the 1943 Maria Montez vehicle White Savage, and even Leni Riefenstahl's legendary White Hell of Pitz Palu. Leading lady Adams, who later professed to have had a great time filming this serial, was the only Universal contract actor in the cast.