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Historia de un Gran Amor was one of the most successful Mexican productions of 1943, a hit with audiences and critics alike. Jorge Negrete plays Manuel, a poor boy of indeterminate lineage who falls in love with a wealthy senorita (Gloria Marin). Told by the girl's father (Julio Villareal) that he isn't a worthy suitor, Manuel vows to make something of himself and return for his love. Years later, a much-richer Manuel rides back into town, only to discover that his sweetheart has married another. But their love is too strong to be impeded by matrimonial bonds, and hero and heroine declare undying devotion to one another. Alas, their romance is foredoomed, thanks to the girl's jealous, short-tempered husband. Historia de un Gran Amor was based on El Nino de la Bola, a novel by Antonio De Alarcon.