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After Jesse (John Stamos) and Joey (David Coulier) prepare a cologne commercial, their client insists upon featuring Jesse in the leading role--wearing practically no clothes, and surrounded by similarly undraped female models. Concerned over the effect that this will have on his fiancee Becky (Lisa Loughlin), Jesse refuses to do what the client wants. This sudden attack of integrity leads to a life-altering (and rather traumatic) experience. Meanwhile, the cure may turn out to be infinitely worse than the disease when Michelle (role shared by the Olsen twins) plays nurse for Steph (Jodie Sweetin), who is confined to bed with a bad cold.