Synopsis by Josh Ralske
This episode features three short segments based on viewer suggestions. In "No Bones About It," a genie comes out of Peter's (voice of Seth MacFarlane) beer bottle and grants him three wishes. His first wish is to see what Kelly Ripa (who does her own voice) is like off the set. He wishes that he had his own theme music. This wish leads to trouble. While Peter enjoys the "traveling music" that plays as he rides the bus, another passenger takes offense, and threatens to "break every bone" in his body. So Peter makes his third wish -- "I wish I had no bones." The Griffin family is so unhappy with Peter's transformation into an amorphous blob that he tries to kill himself by letting himself down the drain. In "Super Griffins," the family is exposed to toxic waste and develops strange abilities. Stewie (MacFarlane) has telekinetic powers, Chris (voice of Seth Green) can conjure fire, Brian (MacFarlane) has super speed, Lois (voice of Alex Borstein) has super strength, Peter can shape shift, and hapless Meg (voice of Mila Kunis) can grow her fingernails really long in an instant. Despite Lois' call to use their powers responsibly, the Griffins soon run afoul of the authorities, and Mayor Adam West (voice of Adam West) exposes himself to toxic waste in order to do battle with them. In "Little Griffins," the characters are all bigheaded children, in some kind of godforsaken amalgam of Muppet Babies and The Little Rascals. Peter and Quagmire (MacFarlane) spend the night in a haunted house to prove to Lois that each is braver than the other. This episode features the voices of professional wrestler Goldberg, Adam Carolla, Michael Winslow, and Regis Philbin.