Lord Doyle (Colin Farrell) is laying low in Macau – spending his days and nights on the casino floors, drinking heavily and gambling what little money he has left. Struggling to keep up with his fast-rising debts, he is offered a lifeline by the mysterious Dao Ming (Fala Chen), a casino employee with secrets of her own.
However, in hot pursuit is Cynthia Blithe (Tilda Swinton) – a private investigator ready to confront Doyle with what he is running from. As Doyle tries to climb to salvation, the confines of reality start to close in.