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Helen (Olympia Dukakis) is an elderly widow who lives a quiet but happy life with her friends and her housekeeper Katie (Della Reese). A dark cloud appears when Helen discovers she has cancer. While receiving treatment, Helen meets Jane (Kelly Rowan), an attractive nurse who happens to be single. Before long, Helen is convinced that Jane is the perfect girl for her son Tom (John Stamos), a lawyer who handles a number of divorce cases and as a result is wary of marriage. Neither Jane nor Tom are entirely convinced they'd be an ideal couple, but Helen will not be denied. After a few dates, it looks like Tom and Jane might end up together after all, until Helen's declining health sends Tom on a mild bender that finds him in bed with another woman when Jane stops by to visit.