After majoring in chemistry and pharmacology at the University of Tennessee, New York-native Samuel G. Engel signed on as an assistant director at Warner Bros. in 1933. Three years later he was invited by old Warners colleague Darryl F. Zanuck to join the producers staff at 20th Century-Fox. Following Navy and OSS service in World War II, Engel returned to Fox, where he rapidly re-established himself as producer and co-writer of My Darling Clementine (1946). He stayed with Fox until 1962, four years before his retirement from the business. From 1950 through 1951, Engel served on the Motion Picture Academy Board; he was vice president of that board from 1952 through 1958, then again from 1959 through 1960. And from 1955 through 1958, Samuel G. Engel was president of the Producers Guild of America.