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The daughter of the fashion editor of Life magazine, Sally Kirkland often appeared in Vogue and other magazines as a model. After high school, she studied with Uta Hagen and Lee Strasberg at the Actors' Studio, then appeared in off- and off-off-Broadway productions; her appearance in Sweet Eros won her a great deal of notoriety (her part required her to sit onstage for 45 minutes, tied up and nude). She debuted on Broadway in Step on a Crack (1962). In 1964 Kirkland became a member of Andy Warhol's Factory. She appeared in a number of underground and avant-garde films, leading to supporting roles in Hollywood films. In 1983 she founded the Sally Kirkland Acting Workshop, a traveling seminar; her workshop emphasized the positive effects of meditation and yoga. For her work in Yurek Bogayevicz's Anna (1987) she received both an Oscar nomination and a Golden Globe Award nomination, plus a Los Angeles Critics "Best Actress" Award. Her subsequent movies have been mostly forgettable actioners and dramas.