- Son of actor and fight master M. B. Shetty.
- Began his career assisting Kuku Kohil during the filming of Phool Aur Kaante (1991), which was also Ajay Devgan's acting debut.
- Directed his first feature film Zameen in 2003, although it was a flop at the box office.
- Directed Chennai Express (2013), which became the highest grossing Bollywood film of all time.
- Became producer by co-producing Singham Returns (2014) under his own banner Rohit Shetty Productions.