One of the salutary byproducts of the TV series Seinfeld is that it created a market in the '90s for sitcoms built around the comedy routines of young, hip New York comics. One of the best of these programs was Mad About You, created by and starring Manhattan-born Paul Reiser. Reiser and Seinfeld share more than a similarity of sitcoms; together with comedians Larry Miller and Mark Schiff, they comprise what has been unofficially dubbed the Four Funniest Men in the World Club, which has met for lunch each New Year's Day for the past several years. Reiser's credentials include a degree from S.U.N.Y.-Binghamton, a short stint as a health food distributor, and a 1982 film debut in Diner. Most of his film roles have been in comedies, though he was effectively cast as a greedy space traveler (who comes to a well-deserved bad end) in 1986's Aliens. Reiser has noted that his weekly series Mad About You, in which he co-starred with Helen Hunt, was based on his relationship with his wife, Paula. In 1995, Paul Reiser took a brief respite from Mad About You to star in the "single dad" comedy Bye Bye Love.
As the new decade began, and Mad About You came to a close, Resier appeared in One Night at McCool's, and four years later realized a personal dream by co-starring with Peter Falk in The Thing About My Folks, a film Resier co-wrote as well. He was interviewed in The Aristocrats, and appeared as himself in Funny People. In 2011 he masterminded the very short-lived NBC sitcom The Paul Reiser Show.