- Decided she wanted to work as a voice actor for cartoons at the age of 8.
- Was a member of The Groundlings for 10 years.
- Earned her first professional voice-over role in a 1979 episode of Scooby-Doo and Scrappy-Doo.
- Played the role of Lucille Ball in Weird Al Yankovic's 1983 music video for "Hey, Ricky!"
- In 1995, was nominated for the award for Voice Acting in the Field of Animation for her role as Dot Warner in Animaniacs at the 23rd Annual Annie Awards.
- Nominated for the award for Voice Acting by a Female Performer in a TV Production for her role as Debbie Douglas in Mission Freakazoid at the 25th Annual Annie Awards.
- Provided the voice for characters in numerous video games, including Kingdom Hearts, Futurama, Epic Mickey, Fallout and The Simpsons Game.
- Has been the voice of many iconic television characters, including Daisy Duck, Wilma Flintstone, Babs Bunny and multiple roles in The Simpsons.