- Named "wittiest" in her junior-high-school yearbook.
- Created sketch-comedy group Ms. Dee, named after her dog, in New York before writing and performing in the one-woman off-Broadway show This Is Where I Get Off.
- In 1996 became the first female correspondent on The Daily Show With Jon Stewart and hosted her own series of interview specials.
- Was a recurring character on the Michael J. Fox sitcom Spin City for two years.
- In 2004 landed a lead role on the short-lived Fox comedy Method & Red, which starred Method Man and Redman.
- Played extremely different moms on Disney's I'm in the Band and MTV's The Hard Times of RJ Berger.
- Is fond of saying that she follows in "the rich tradition of Episcopalians in comedy."