- Grew up believing that his father was actor Robert Vaughn until a paternity test proved otherwise; he later legally changed his name to Matthew Allard de Vere Drummond to reflect his parentage.
- Godfather is Peter Morton, movie producer and cofounder of the Hard Rock Café.
- In 2004, made his directorial debut with Layer Cake, a thriller about a retiring drug dealer who's forced to take another assignment.
- Was set to direct X-Men: The Last Stand (2006) but left the project due to script concerns; eventually directed the prequel X-Men: First Class (2011).
- Is color blind.