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A pretty brunette leading lady of the 1920s, Ann May was, according to her official studio biography, a "1916 graduate of the Schuster-Martin School of Dramatic Art" and a member of a local Cincinnati stock company for one year prior to making her screen debut in 1919. May was the typical screen ingenue and extremely well-cast opposite the likes of Charles Ray (Peaceful Valley, 1920), Wheeler Oakman (The Half Breed, 1922), and Fred Thomson (Thundering Hoofs, 1924). The latter, in which May played a proud senorita, remains one of Thomson's few surviving Westerns. Ann May met her husband, screenwriter C. Gardner Sullivan, on the set of The Dangerous Maid (1923), and retired in 1925.