John S. Robertson began his two-decade Hollywood career at Vitagraph in 1915. Robertson did some acting and scriptwriting before concentrating on directing. His silent-film directorial credits include the 1920 John Barrymore version of Dr. Jekyll and Mr. Hyde, Mary Pickford's Annie Laurie (1927), and Garbo's The Single Standard (1928). He was also instrumental in building up the careers of several promising newcomers, notably actress May McAvoy (Sentimental Tommy, The Enchanted Cottage). During the talkie era, he spent most of his time at RKO Radio, helming such films as Little Orphan Annie (1932) and Grand Old Girl (1935). John Stuart Robertson's final film was the 1935 Shirley Temple vehicle Our Little Girl (1935).