An actress who commenced onscreen roles in late adolescence, Lizzy Caplan initially specialized in playing teenagers and young adults in tough-natured and slightly edgy material. Caplan landed many of her earliest assignments on the small screen, in telemovies such as the 2000 From Where I Sit and the 2002 Everybody's Doing It, and made repeat appearances on such series programs as Smallville, Freaks and Geeks, and Tru Calling. Not long after, the young performer joined the cast of Mark Waters and Tina Fey's satirical big-screen comedy Mean Girls (2004), as misfit high-school student Janis Ian. Also in 2006, Caplan scored a regular role on the sitcom The Class. In 2008, Caplan made a memorable apperance in the Matt Reeves' sci-fi thriller Cloverfield as Marlena, one of the victims of a city-wide rampaging monster, followed by a memorable run as a hippie hooked on vamprie blood on True Blood. TV would prove a good fit for the actress, who also proved an impressive comedian with starring roles on shows like Party Down, Childrens Hospital, and New Girl, In 2012, Caplan headlined a couple of girly, indie-ish films, Save the Date and Bachelorette, before taking on her highest-profile role to date- sex researcher Virginia Johnson on Showtime's Masters of Sex. Caplan was nominated for an Emmy for her work in the show. In her downtime from the series, Caplan found time to squeeze in some film work, including 2015's Christmas comedy The Night Before and 2016's Now You See Me 2.
Biography by Nathan Southern
- Made TV debut as Sarah in 1999 on the series Freaks and Geeks.
- Played a mean girl named Janis Ian in the 2004 hit comedy Mean Girls.
- In 2006, listed as one of Variety's Top 10 Actors to Watch.
- Blindly auditioned for the film Cloverfield and accepted a role before knowing what the film was about.
- Appeared in the first season of True Blood as Amy, Jason Stackhouse's drug-addicted girlfriend.