Universal's "Frankenstein" series descended from the "A" to the "B" category with The Ghost of Frankenstein, though production values were still well above average and the cast is first-rate. The story picks up where Son of Frankenstein (1939) left off, with both the Monster (Lon Chaney Jr.) and his crazed companion Igor the shepherd (Bela Lugosi) being chased out of the village of Frankenstein by the irate citizens (actually both Monster and Igor had been killed at the end of Son of Frankenstein, but that's neither here nor there). The gruesome twosome head to the tiny Balkan community where dwells the son (Sir Cedric Hardwycke) of the original Dr. F. At the urgings of both Igor and the disgraced Doctor Bohmer (Lionel Atwill), Frankenstein Jr. is coerced into repeating his father's experiment of placing a fresh brain in the head of the monster. Seeking vengeance against his enemies, Igor wants to have his own brain grafted into the Monster's skull, but the big lug himself has other ideas: having befriended cute little Cloestine (Janet Ann Gallow), the only person in the village who doesn't fear him, the Monster insists upon receiving Cloestine's brain. In the end, however, Dr. Frankenstein goes with Igor's graymatter-and the result is disaster for practically everyone in the cast. Highlights of this 68-minute scarefest include Lionel Atwill's outraged reaction when he is reminded of the "slight miscalculation" that ruined his medical career, and the uncredited appearances of several "Frankenstein" movie veterans, including Dwight Frye, Holmes Herbert and Lionel Belmore.
by Hal Erickson synopsis