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The Saint Strikes Back was the second in the series of films featuring Simon Templay, better known as The Saint, and the first to star George Sanders in the role. Val Travers (Wendy Barrie) is the daughter of a police detective who killed himself after being dishonorably let go from the San Francisco Police Department, due to allegations that he was a member of a gang led by the mysterious criminal mastermind known only as Waldeman. Hoping to clear her father's name, Val has assembled a gang of minor criminal types to track down Waldeman, which puts her in trouble with the police. Templar crosses tracks with Val and, after hearing her story, believes that her father was framed, most likely by someone else working in the police department. Cullis, one of department's chief criminologists, dismisses this suggestion and implies that Templar might be Waldeman. Templar's investigations eventually find the real culprit and exonerates Val's father.