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In this installment of the long-running Santo series from Mexico, the titular masked hero is summoned to solve a long string of unsolved serial murders. Santo soon finds himself attempting to counter the vile Malkosh, who commits his killings with the help of a blob-like creature that swallows its victims alive. The plot thickens when it becomes apparent that another villain, the psychopath Boris Licur, has kidnapped the only individuals seemingly able to destroy the creature: scientist Dr. Bernstein and his daughter. Santo must act quickly, before Licur wrests control of the creature and takes over the world.