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Now that she is engaged to Tony (Larry Hagman), Jeannie (Barbara Eden) is determined to befriend the neurotic Amanda Bellows (Emmaline Henry),the wife of Tony's perennial nemesis Dr. Bellows (Hayden Rorke). Jeannie's first step is to present Amanda with a magical beauty cream which transforms the middle-aged psychiatrist's wife into a gorgeous young woman (played by Laraine Stephens). The plan backfires when Roger (Bill Daily) falls madly in love with the "new" Amanda, blissfully unaware of her husband's identity.