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While taking the AP Calculus exam, high-school student Matt Davis (John Patrrick Amedori) collapses. Discovering that Matt has been lethally poisoned, House (Hugh Laurie) suspects that the boy has been doing drugs at home. When another student exhibits the same symptoms, however, it is obvious that the source of the poison is the school testing room--but how can this be? Meanwhile, another clinic patient, 82-year-old Georgia Adams (Shirley Knight), suddenly develops an uncontrollable sex drive...and an insatiable lust for Dr. House!