Dexter's Laboratory: Space Case (1996)

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After working tirelessly to make contact with aliens from outer space, Dexter is finally visited by a trio of aliens. While showing them around the lab, they tell Dexter they intend to take him away for further experimentation. Dee Dee shows up at that moment, and, thinking quickly, Dexter sends her along with them. At first he's glad to be rid of his annoying sister, but he begins to feel pangs of guilt and takes off to save her. (Original air date: December 18, 1996.)