- Left home at age 14 to make money for his family as a boxer.
- Made his professional boxing debut at age 16.
- Has been named WBC champion in the super featherweight, flyweight, lightweight, welterweight, and super welterweight classes, including four successful defenses of his welterweight title.
- Named the Boxing Writers Association of America's Fighter of the Year several times, the first in 2006.
- Released his first album, Laban Nating Lahat Ito, in 2006.
- Even though he was not competing at the games, was the flag bearer for the Philippines at the opening ceremonies of the 2008 Summer Olympics in Beijing.
- Named Boxing Writers Association of America's Fighter of the Decade for 2000-09.
- First eight-division world champion in boxing history.
- Elected to the Philippine House of Representatives at Sarangani in 2010 on his own ticket, the People's Champ Movement.
- In 2014, was named head coach and a player of the Kia Sorento from the Philippine Basketball Association.
- Named an Ambassador for Habitat for Humanity Philippines.