Academy of Television Arts and Sciences
| Nominated |
Outstanding Guest Actress in a Comedy Series 30 Rock [TV Series] |
2008 |
| Won |
Outstanding Lead Actress in a Comedy Series Nurse Jackie [TV Series] |
2010 |
| Nominated |
Outstanding Lead Actress in a Drama Series The Sopranos [TV Series] |
2007 |
American Film Institute
| Won |
Best Female Actor in a Television Series The Sopranos [TV Series] |
2001 |
Hollywood Foreign Press Association
| Nominated |
Best Performance by an Actress in a Television Series - Drama The Sopranos [TV Series] |
2001 |
| Nominated |
Best Performance by an Actress in a Television Series - Musical or Comedy Nurse Jackie [TV Series] |
2010 |
| Won |
Best Performance by an Actress in a Television Series - Musical or Comedy The Sopranos [TV Series] |
2002 |
Independent Spirit Awards
| Nominated |
Best Actress Laws of Gravity |
1992 |
Los Angeles Film Critics Association
| Won |
Best Supporting Actress Sunshine State |
2002 |
Screen Actors Guild
| Nominated |
Best Actress in a Comedy Series Nurse Jackie [TV Series] |
2009 |
| Nominated |
Best Actress in a Drama Series The Sopranos [TV Series] |
2000 |
| Won |
Best Female Actor in a Drama Series The Sopranos [TV Series] |
1999 |
| Won |
Best Performance by an Actress in a Television Series - Drama The Sopranos [TV Series] |
2002 |
