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A drifting young man named Ryan (Elijah Wood) is asked to watch his neighbor's dog, Wilfred---who looks like a dog to everyone else but appears as a man (Jason Gann) in a dog suit to Ryan---in the opener of this live-action comedy, which is adapted from an Australian series and also starred Gann as wisecracking and pot-smoking Wilfred. Ryan could use a pick-me-up: He's supposed to begin a boring job and he just attempted suicide.