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A squadron of top-rank fighter pilots are trained for any emergency that might befall the United States, and their skills are put to the test when an internationals weapons ring gains access to a cache of nuclear weapons. Before the "First Strike" team can crush their enemy, bombs destroy several major cities in the U.S. and around the world, taking thousands of lives, including the squadron's leader. With a new and untested commander, the "First Strike" squad must race against time to find the remaining weapons before more lives are lost.