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In the first episode of a two-part story, Drew (Drew Carey) begins dating a girl named Rachel (Ileana Douglas), only to be warned by Lewis (Ryan Stiles) that Rachel is actually an activist protesting a current DrugCo project, and may be playing up to Drew merely to get secret information. Though it turns out that Lewis is right, Rachel's motives are not quite as cold-blooded as they seem. Be that as it may, whatever DrugCo is cooking up just might be the reason that Drew and his friends have suddenly begun to glow in the dark!