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Cesar Romero plays the Cisco Kid, who may be a bandit but is no kidnapper. This being the case, Cisco and his pal Pancho (Chris-Pin Martin) offer to help round up a vicious frontier kidnapping ring. The leaders turn out to be several solid citizens of a western town, but Cisco knows a rat when he smells one. Mary Beth Hughes plays a saloon girl with whom Cisco dallies before deciding upon good-girl Lynne Roberts. Ride on Vaquero was the last of 20th Century-Fox's Cisco Kid B series, and the last to star Cesar Romero.