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Malaria still ranks as one of the major scourges of humankind, and, along with tuberculosis, kills more people than any other disease. While prompt treatment can result in cures, this is often not possible in the poorer countries where malaria is frequently found. Most cases occur in sub-Saharan Africa, where extreme poverty and the necessity to work during the rainy season exposes the population to malaria-bearing mosquitoes. Perspective: Malaria reviews the possible methods for prevention of the disease, including the use of insecticide-soaked mosquito nets.