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Pro baseball pitcher Hank Wiggen (Scott Foley) insists he is not a drug user, but the evidence indicates otherwise: His bones are brittle to the point of disintegration, and his kidneys have started to fail. Astonishingly, the clinic's lab test indicate that Wiggen is not currently on steroids, nor is he suffering from cancer as the symptoms might also suggest. House (Hugh Laurie) must figure out what's really wrong with Wiggen before the ballplayer's girlfriend Lola (Meredith Monroe) aborts her pregnancy in order to donate her kidneys. And in another development, Foreman (Omar Epps) is secretly dating a sexy drug representative (Salli Richardson-Whitfield), while Wilson (Robert Sean Leonard) is seeing one of House's former lovers. Somehow or other, this all winds up at a monster-truck rally!