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Faced with the choice of firing one of his team or losing his own job, House (Hugh Laurie) is given a way out by Vogler (Chi McBride). If he will give a speech on behalf of a new drug developed by Vogler's pharamaceutical firm, House will be completely off the hook. The upshot of all this only serves to deepen the animosity between House and Vogler--but in the meantime, the doctor must tend to the business at hand, including a senator (Joe Morton) with presidential aspirations who is diagnosed with AIDS, and a young woman (Missy Crider) who insists that she can't have suffered a miscarriage because she hasn't had sex in over a year. As expected, both of these patients will soon develop a whole set of confusing and contradictory symptoms...but no one expects the startling turn of events at episode's end!