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He Loves Me ... He Loves Me Not is a black comedy with a dramatic twist. Talented art student Angélique (Audrey Tautou) is wildly in love with Loïc (Samuel Le Bihan of Brotherhood of the Wolf), a married cardiologist whose wife, Rachel (Isabelle Carré) is expecting their first child. She sends him mash notes and gifts, and tells her friend, Héloïse (Sophie Guillemin of With a Friend Like Harry...) that, despite appearances, Loïc plans to leave his wife. Angélique also ignores the attentions of her lovesick friend, David (Clément Sibony), who begins to resent the way Loïc treats Angélique. As Angélique grows less discreet in her affections, Loïc's home life begins to fall apart. His wife grows suspicious, and then miscarries. His career is jeopardized when a patient accuses him of assault. All the while, Angélique is desperate to be by his side. About 40 minutes in, writer/director Laetitia Colombani's film reverses perspective, showing the preceding events from Loïc's (very different) point-of-view.