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Paladin (Richard Boone) intervenes when he witnesses a gang of toughs harrassing Joseph Whitehouse (Anthony Caruso), a missionary-educated Cherokee who owns a thriving cattle ranch. Investigating the situation, Paladin learns that Whitehorse and his wife Martha (Carol Thurston) have been targeted for persecution by Indian-hating rancer Clyde McNally (Leo Gordon), who claims that the Cherokee couple's cattle are spreading disease. As the story progresses, it appears that Paladin has opted to side with McNally against the Whitehorses--but as often happens in this series, appearances can be deceiving!