Synopsis by Hal Erickson
Suffering from the mother of all hangovers, George (T.R. Knight) is in no shape to meet his new father-in-law (Hector Elizondo)--especially after spending the night with a woman other than his wife. Alex (Justin Chambers) helps Jane Doe (Elizabeth Reaser) select her "new look" after she completes her surgery. Izzie finds out about Meredith's (Ellen Pompeo) drinking problem, all the while keeping mum about a secret of her own. And the arrival of Cristina's (Sandra Oh) former lover Colin Marlow (Roger Rees) seriously compromises her relationship with Burke (Isaiah Washington).