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Debuting over MyNetworkTV on September 5, 2006, Desire was one of two nightly hour-long continuing dramas seen over the fledgling network during its first season on the air; both this series and its companion show, Fashion House, were inspired by the Spanish-language "telenovela" genre, and both were filmed in San Diego. The principal players in Desire included the Thomas brothers, Alex (Zack Silva) and Louis (Nate Haden), who had to give up running their restaurant in Bayonne, NJ, when the headstrong Louis was caught in bed with the daughter of a gang boss. Fleeing the gangsters' wrath, the Thomas boys relocated to California, where they went to work for sexy Andrea Zavatti (Michelle Belegrin), heiress to a huge restaurant fortune. Having lost her best employee and boyfriend George (Tomy Dunster) to her false friend Suzy (Vivian Gray), Andrea's affections were torn between the affable Alex and the ruthless Louis for the balance of the series. Others in the cast included Andrea's calculating half-sister, Victoria Marston (Sofia Milos), vengeful mob chieftain Joey Gamarra (Chris de Rose), and the Thomas brothers' long-suffering mother, Rita (Eliana Alexander). Telecast on a Monday through Friday basis, with a weekend "recap," Desire was destined for a 13-week, 65-episode run, at which point MyNetwork would replace it with a new nightly soaper, Wicked Wicked Games.