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A serial killer with an odd signature (surgically removing the victim's teeth, leaving behind a medallion of the Madonna) may be back in action again. In the past, the investigation of the killer's activities have always been shut down on the orders of Lydecker (John Savage), and Max (Jessica Alba) and Logan (Michael Weatherly) want to find out why -- though, truth be told, Max already has a disturbingly good idea about Lydecker's motives. Nana Visitor makes her first appearance as Lydecker's sinister boss, Manticore director Elizabeth Renfro (aka "The Dragon Lady").