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The title insurrection in this low-budget Whip Wilson Western consists mainly of Iron Eyes Cody, who is conspiring to raid the wagon trains with crooked sheriff Marshall Reed and nefarious Indian agent Forrest Taylor. Investigating the presumed revolt, the whip-wielding Wilson and grizzled sidekick Andy Clyde, United States Marshals, are aided by Canyon City's kindhearted judge (Sam Flint and his pretty daughter Lois Hall. The latter, almost needless to say, is kidnapped by the gang but rescued in the nick of time by Whip, whose famous weapon of choice disarms the crooked sheriff. By no means the worst of Wilson's low-budget oaters for Monogram, Cherokee Uprising was filmed at the picturesque Iverson Ranch in Chatsworth, California.