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In this episode of Biography, the life and times of Don Knotts is examined. A comic actor, Knotts is probably best known for his portrayal of Barney Fife, the bumbling deputy on the Andy Griffith Show. However, Knotts' brand of over-the-top comedy concealed a deeply troubled man, a man who struggled through much adversity early in his career, and with near crippling bouts of hypochondria for most of his life. Interviews with friends such as Tim Conway, Andy Griffith, and Steve Allen give poignant insight into a painfully shy man.