Escaping the clutches of an illicit arms dealer, Sydney (Jennifer Garner) takes on her next counterespionage assignment. Her mission transports her to Madrid, where she is to purchase a 500-year-old drawing by the remarkably prophetic Renaissance artist Milo Rambaldi -- a sketch containing a portion of a code vital to the operation of a deadly nuclear device. In the course of events, Sydney continues to press her secret-agent father, Jack (Victor Garber), for details surrounding the death of her mother, Laura.