In the sequel to Waxwork, young Mark Loftmore (Zach Galligan) and his girlfriend Sarah (Monika Schnarre) manage to escape the deadly wax museum before it is destroyed. However, one deadly wax hand escapes destruction and follows Sarah home, murdering her stepfather before she manages to destroy it. When Sarah is accused of the murder, she and Mark must travel back in time to stop the still-present evil.