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Screenwriter Richard Alfieri and director Arthur Allan Siedelman adapt Anton Chekhov's classic stage play The Three Sisters to the screen in this film starring Mary Stuart Masterson, Maria Bello, and Erika Christensen as the titular siblings. Upon departing from Charleston, SC, to further their education at a prestigious Manhattan college, sisters Marcia (Bello), Olga (Masterson), and Irene (Christensen) soon become lost in fantasies of what their lives may have been to the point where they are unable to affect change in their real lives. As the three sisters gradually open up to each other and their brother, Andrew (Alessandro Nivola), the specter of their deceased father soon lifts, leaving the nostalgic siblings to realize that the only way to confront the brutal realities of life is through honesty and understanding.